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Popular Resources in Protease Inhibitor Series

MG-132

CAS No. 133407-82-6

MG-132 is surely an inhibitor of proteasome with IC50 of 100 nM within a cell phone-free of cost assay, and also inhibits calpain with IC50 of 1.2 μM.

Bortezomib

CAS No. 179324-69-7

Bortezomib (PS-341) is truly a potent 20S proteasome inhibitor with Ki of .6 nM in a mobile-free of charge assay.

Carfilzomib

CAS No. 868540-17-4

Carfilzomib (PR-171) is surely an permanent proteasome inhibitor with IC50 of 5 nM in ANBL-6 cellular materials, showcased preferential in vitro inhibitory strength versus the ChT-L process inside the β5 subunit, but very little if any influence on the PGPH and T-L steps.

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