Cyclopamine Chemical product DesignCyclopamine
Cyclopamine is truly a unique Hedgehog (Hh) signaling pathway antagonist of Smoothened (Smo) with IC50 of 46 nM in TM3Hh12 cells.
Assessment spotlight: Connection with Cyclopamine encourages pancreatic enlargement in embryonic ladies. (Kim SK, et,al. PNAS, 1998, 95: 13036-13041.)
This product can be found in : Bioactive Component Local local library, Organic and natural Component Nearby local library
TWS119 Substance StructureTWS119
TWS119 is actually a GSK-3β inhibitor with IC50 of 30 nM inside the mobile phone-totally free assay able to inducing neuronal differentiation and may even be appropriate to originate mobile phone biology.
Assessment highlight: TWS119, a 4,6-disubstituted pyrrolopyrimidine that could cause neurogenesis in murine ESCs. (Ding S, et,al. PNAS, 2003，100(13): 7632-7637. )
The product is made up of in : Bioactive Compound Nearby local library
Nicotinamide Compound PlatformNicotinamide
Nicotinamide (Vitamin supplement B3), a normal water-soluble nutritional, is unquestionably an productive part of coenzymes NAD and NADP, and likewise serve as an activator of sirtuins.
Analysis highlight: Nicotinamide improved the produce of differentiation of Embryonic Come Cells to pancreatic endocrine tissues (Lumelsky N,et,al.Investigation, 2001, 292(5520): 1389-1394 )
The product contains in : Approved Drug Library, Regular Ingredient Series
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Capabilities 640 all-normal ingredients
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