MG-132 CAS No. 133407-82-6
MG-132 is an inhibitor of proteasome with IC50 of 100 nM within a cellular-totally free assay, as well as inhibits calpain with IC50 of 1.2 μM.
Bortezomib CAS No. 179324-69-7
Bortezomib (PS-341) is actually a potent 20S proteasome inhibitor with Ki of .6 nM in a cellular-free of charge assay.
Carfilzomib CAS No. 868540-17-4
Carfilzomib (PR-171) is undoubtedly an irreversible proteasome inhibitor with IC50 of <5 nM in ANBL-6 cellular material, displayed preferential in vitro inhibitory strength from the ChT-L activity inside the β5 subunit, but little if any result on the PGPH and T-L actions.
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