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Multiple-kinase Inhibitor

Flumatinib

Flumatinib is really a multiple-kinase inhibitor with IC50 Principles of 1.2 nM, 307.6 nM and 2662 nM for c-Abl, PDGFRβ and c-Package correspondingly.

Relevant Products: EP Z020411 2HCl

FAAH Inhibitor

BPF-04457845

BPF-04457845 is truly a highly efficacious and discerning FAAH inhibitor with IC50 beliefs is 7.2±0.63 nM and 7.4±0.62 nM for hFAAH and rFAAH, respectively.

Relevant Products: LTI-291,Donepezil

SIRT6 Inhibitor

OSS128167

OSS128167 is actually a distinctive SIRT6 inhibitor with IC50 morals of 89, 1578 and 751 μM for SIRT6, SIRT1 and SIRT2, correspondingly.

Related Merchandise: Quinine dihydrochloride

CRF1 Receptor Antagonist

CP 376395

CP 376395 can be a highly effective and picky Corticotropin supplying aspect 1 (CRF1) receptor antagonist.

Appropriate Products: GNE-617 , OSS128167

TMEM16A Inhibitor

CaCCinh-A01

CaCCinh-A01 is certainly an inhibitor of both TMEM16A and calcium supplements-switched on chloride funnel (CaCC) with IC50s of 2.1 and 10 μM, respectively.

Associated Products: IPTG ,GNE-617

Piece Catalog

Chemical Series

45 kinds of compound libraries for top rated throughput confirmation and high content articles verification.

Investigation Areas

Proteases/Proteasome

Chromatin/Epigenetic

JAK/STAT signaling

Tyrosine Kinase/Adaptors

PI3K/Akt/mTOR Signaling

MAPK Signaling

Apotosis

Ubiquitination

Angiogenesis

Immunology/Irritation

DNA Cause harm to/DNA Servicing

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