Multiple-kinase Inhibitor
Flumatinib is really a multiple-kinase inhibitor with IC50 Principles of 1.2 nM, 307.6 nM and 2662 nM for c-Abl, PDGFRβ and c-Package correspondingly.
Relevant Products: EP Z020411 2HCl
FAAH Inhibitor
BPF-04457845 is truly a highly efficacious and discerning FAAH inhibitor with IC50 beliefs is 7.2±0.63 nM and 7.4±0.62 nM for hFAAH and rFAAH, respectively.
Relevant Products: LTI-291,Donepezil
SIRT6 Inhibitor
OSS128167 is actually a distinctive SIRT6 inhibitor with IC50 morals of 89, 1578 and 751 μM for SIRT6, SIRT1 and SIRT2, correspondingly.
Related Merchandise: Quinine dihydrochloride
CRF1 Receptor Antagonist
CP 376395 can be a highly effective and picky Corticotropin supplying aspect 1 (CRF1) receptor antagonist.
Appropriate Products: GNE-617 , OSS128167
TMEM16A Inhibitor
CaCCinh-A01 is certainly an inhibitor of both TMEM16A and calcium supplements-switched on chloride funnel (CaCC) with IC50s of 2.1 and 10 μM, respectively.
Associated Products: IPTG ,GNE-617
Piece Catalog
Chemical Series
45 kinds of compound libraries for top rated throughput confirmation and high content articles verification.
Investigation Areas
Proteases/Proteasome
Chromatin/Epigenetic
JAK/STAT signaling
Tyrosine Kinase/Adaptors
PI3K/Akt/mTOR Signaling
MAPK Signaling
Apotosis
Ubiquitination
Angiogenesis
Immunology/Irritation
DNA Cause harm to/DNA Servicing
See Far more…
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